Epinephrine - As a result of likely for promethazine to reverse epinephrine’s vasopressor effect, epinephrine should NOT be applied to take care of hypotension affiliated with promethazine overdose.
The mix of promethazine hydrochloride and codeine phosphate is contraindicated in pediatric sufferers below 6 yrs of age. Concomitant administration of promethazine goods with other respiratory depressants has an association with respiratory despair, and sometimes Loss of life, in pediatric sufferers. The Affiliation does indirectly relate to individualized excess weight-based mostly dosing, which could in any other case allow Secure administration.
individuals who will be allergic to promethazine, any of your components in promethazine, or to other phenothiazines
The diagnostic evaluation of clients using this type of syndrome is difficult. In arriving in a analysis, it is important to detect instances where the clinical presentation incorporates both equally really serious clinical illness (e.
For preoperative medication children have to have doses of 0.five mg for each pound of body bodyweight together using an properly lessened dose of narcotic or barbiturate and the right dose of the atropine-like drug.
Narcotic analgesics cross the placental barrier. The nearer to shipping as well as the larger the dose utilised, the bigger the possibility of respiratory despair in the newborn. Narcotic analgesics should be avoided all through labor if delivery of the premature infant is predicted.
Unresponsive Cough The dosage of Promethazine HCl and Codeine Phosphate Oral Answer shouldn't be amplified if cough fails to respond; an unresponsive cough must be reevaluated in five days or faster for doable fundamental pathology, which include foreign overall body or lower respiratory tract illness [see Dosage and Administration (two.three)].
Low hypertension. A unexpected drop in blood pressure can come about in lots of people for the duration of remedy with Promethazine Hydrochloride and Codeine Phosphate Oral Option which may possibly bring about you to definitely come to feel dizzy, faint, lightheaded, or weak, particularly when you rise here up (orthostatic hypotension). Your risk of having this issue might be elevated if you are taking Promethazine Hydrochloride and Codeine Phosphate Oral Resolution with particular other medicines that reduce blood pressure.
Promethazine is contraindicated in comatose states, As well as in men and women identified for being hypersensitive or to obtain experienced an idiosyncratic reaction to promethazine or to other
The following laboratory checks could possibly be influenced in patients that are getting therapy with promethazine HCl:
Major breathing problems. Promethazine HCl Oral Answer shouldn't be Employed in people with very poor lung function like Persistent obstructive lung disease or respiratory difficulties while sleeping (rest apnea.)
The diagnostic evaluation of people using this syndrome is challenging. In arriving in a prognosis, it is crucial to recognize instances where the medical presentation consists of each major professional medical ailment (e.
The mix of promethazine hydrochloride and codeine phosphate is contraindicated in pediatric individuals below 6 a long time of age, for the reason that The mix may perhaps induce fatal respiratory melancholy Within this age population.
Put the mixture within a container for instance a sealed plastic bag and throw it absent within the domestic trash. You may as well observe your state or community tips regarding how to safely toss absent Promethazine Hydrochloride and Codeine Phosphate Oral Remedy.